The Comparison of Different Risk Factors which Result in Endothelial Damage Leading to Diabetic Microangiopathy
نویسنده
چکیده
Chronic endothelial damage plays an important role in the development of angiopathy in diabetes mellitus (1). Since diabetic nephropathy is not determined in forty percent of patients with nonregulated type I diabetes mellitus, it is conceived that the role of hyperglycemia in angiopathy development is not very important. In addition to hyperglycemia, factors such as hypertension, hypercholesterolemia, hyperuricemia and genetics accelerate the development of angiopathy. Once diabetic nephropathy is developed, its progression
منابع مشابه
Endothelial dysfunction and pathogenesis of diabetic angiopathy.
OBJECTIVE AND METHODS To review, from the clinical perspective, the contribution of dysfunction of the vascular endothelium to the pathogenesis of diabetic micro- and macroangiopathy. RESULTS Available data indicate that endothelial dysfunction in diabetes complicated by micro- or macroalbuminuria (renal microangiopathy) is generalised. The close linkage between microalbuminuria and endotheli...
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